ULTRASOUND AS FIRST LINE STEP IN ANAEMIA DIAGNOSTICS

Cranial Ultrasound as a First-Line Imaging Examination for Craniosynostosis.

BACKGROUND Radiography, typically the first-line imaging study for diagnosis of craniosynostosis, exposes infants to ionizing radiation. We aimed to compare the accuracy of cranial ultrasound (CUS) with radiography for the diagnosis or exclusion of craniosynostosis. METHODS Children aged 0 to 12 months who were assessed for craniosynostosis during 2011-2013 by using 4-view skull radiography a...

Current and future diagnostics of anaemia

1) Anaemia is associated with detrimental effects on mortality and should therefore not be considered an innocent consequence of aging. (this thesis) 2) Mean corpuscular volume (MCV) has very little predictive value in the evaluation of anaemia in general practice and should be removed from anaemia diagnostics. (this thesis) 3) In the Netherlands, there is a limited adherence to the gold standa...

Orbital Subperiosteal Hematoma in the Newborn Causing Unilateral Proptosis: Ultrasound as First-Line Imaging Modality

Proptosis in the neonatal period is relatively infrequent and has diverse underlying etiologies. One of the more common causes appears to be orbital subperiosteal hematoma. Early detection, differentiation from other causes, and regular follow-up are essential as loss of vision can occur. We describe two cases of neonatal proptosis caused by orbital subperiosteal hematoma highlighting different...

Toward the introduction of Contrast Enhanced Ultrasound as first line diagnosis in focal liver lesions.

Haemolytic anaemia as a first sign of Wilson's disease.

A 19-year-old female presented with haemolytic anaemia and subsequently developed liver failure. This raised suspicion of Wilson's disease, which was confirmed by Kayser-Fleischer rings, a low ceruloplasmin level, raised 24-hour urinary copper excretion and two mutations in the 'Wilson gene'. She was successfully treated with D-penicillamine and zinc. In young patients with unexplained haemolys...